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Dissolution testing is used to measure the release rate of an active component from a solid dosage form under controlled conditions. This technique is used to assess the performance of tablets, capsules, films and other solids.
Dissolution testing is useful for:
- Guiding formulation development
- Assessing the quality of a sample by determining whether the release of active from the formulation is within acceptable limits (often used for release and stability testing)
- Comparing finished products with different formulations
- Confirming the acceptability of changes to manufacturing procedures during scale-up or post-marketing changes
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